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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28d0c602adc9f85e46edea6256b680b4e230f0a8dc6525f3853a746aa28ee872' 
  AND token = 'ZDUzsrA7NJrm0fPb25ySUN64Edz1OjLcTjYSRjUaOok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}