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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f19cba6cdeb8ea05144c2654fdb7727ead8de6b75244c96af171b43665f11c' 
  AND token = 'bDv7ayscaA7VBLdGaIWfQotkkXYmESrh2LSUOgdCFrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}