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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a8baef35829062ad3695a81a3d7950201df0d977ba0665db63f87142e8a8cc5' 
  AND token = 'Pv0W4F9Y28upx4NE7d5m5G5gyrQrobA5LgvCSoY50OM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}