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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d1a7d16ea077c512134d9472246c7490f92b0046b25370b1292c24a7f679c1' 
  AND token = 'zxMn+jb3m/nSSCfCyCZD6yieZ/odHkTcBFXeq5jXdq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}