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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50480462669be2657298f0f4a7b00d70122bce841d9df18b409e14c091803610' 
  AND token = 'bR1roBe2ZnG12nXFJulX43/u07qYulgV31zWVG7Eu/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}