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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a4a306fc150c653a0ae86dc9c5421c0d0fcdbaab4a83fa35345342507972440' 
  AND token = 'AclI9jZmM2FAOQqIspBGbEKCXWxN9BFqJQajNFJg4gU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}