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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1492bed2a13d3436e8d5e9f363a21bd0678518156741c7581927312f7e2f8c6' 
  AND token = '4MFY6i7uWbdeeZ2YCtfUb/eQS9Uj4uGnpvYJwmw36OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}