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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6412450718ac540ebfd668c405e17dbb551170b0b14aa8e1d86a7846cadb0f87' 
  AND token = 'yxv7m6LEbK/B0YbNeT48BHQlNsSqhB2rwSN0YlPvpnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}