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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '950120fdf076cadfa4f91e7a5676552ec2b7d6329b8dc22d655f8f2439e08044' 
  AND token = 'OmNY3VP3+SQQHpn9UIqAiCuUA5JiFXKEk6y00B+PRPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}