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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a437e03678095c1d26a96476b22350ca078ffe3946c2e959afa66a6cdc666d02' 
  AND token = 'm3nRJ7SjRpgToTiWTucbDI/hxeAkwNqal9HtaYm6+I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}