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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e74bb8b411d3ca092f9d746aab5ff6dc901e245081101d97610c76c4acf1dc1f' 
  AND token = 'Zti9tjyfAm3qiIMZTJTAPNMNtrhE3h36Whlgjxhb1Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}