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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4008e23c941e4b38eae2bdfd9d8224ba6db432da25d6749eb2c09fc173f6de8' 
  AND token = 'A//skho8DjMYaaJzIpg7d9pqYn4xxc14w6lSM3n+1aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}