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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f75e5ba86369b16e273fcacbee0c39d2a645781be69f5a7e00a59dfd5bdc2187' 
  AND token = 'RVn3TrxNIvteSVNFf9rLGDKasrw/g9m2MX/55nREW6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}