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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '107e4689c3a368c428ffc44c364c26315025160c92a1a6aedc39cb83105b55d3' 
  AND token = '2PhBf1g4QklgN41VurgNmW3/aVrKF3TPrv9f7t/zbaQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}