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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c5f870529f4dad798990a1dc73f681464177c7fbde4129902876dc635d0aef3' 
  AND token = 'kewisUisvVterw+tG3zEPIwko6mHkBRqhzbeFFeGMf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}