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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8422070e9512363807f6c91999c144d60b3db42c3099c9e198dc104f8f3bb772' 
  AND token = 'fuy64tjWFRjn7XRyB8MCQOgBrfk3Rj7GkYlgvuXoAcI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}