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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b8d72a768b012908662b5dd9bdf017f34ce847a400a93cd6aee4e01ee2640d3' 
  AND token = '2voxAtQ8zg4x1D9vBEc2cwVvC/rl3ZiDV5fgOK/uccE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}