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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8c53df6fdbf798e23003428ca852653664ce5b3a222349ceb20f911a87fb22' 
  AND token = '1arQIb3UBE3vbiV6TqJ4Vf8cxLYXSBz5j7h9kEV9Gks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}