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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b399eeca40156a25dc1cdaed963044165ae07dbfe93db667be7b19d5c5a983' 
  AND token = 'BfkICA+/rsXw/Ftbbaf9rxV6GrTMSXZTypYZ+Ij5yVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}