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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f6b0e9eb9a91d9e7f4a3f5d70b0169f1d893dd8729980f3800b77b5b54417a' 
  AND token = 'ErlBhSQVbijqvitTsymUJ4WO+dYjl0TVONWyIn9WRoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}