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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57e9a439c524e49d5fc304862b1967a3884c3dd6e280199f3d3d00fac075707a' 
  AND token = 'XFGi0a02HQY+cLdHLHTLlQ4Rp/xM8Hd+zm6m6fxVViU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}