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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'deb6d037bd133eac2ef0379fb28428dc3df9d367d68c49d0fb703d000ca5e015' 
  AND token = '53be4s2b4p9uBj4RpNq6iD+9Yv9Q5h0ZTd6JWyoNCHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}