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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a46ab4f4abec30dabb8d3a99581144a44a1f8728757d0621ee0e55cad4dd77' 
  AND token = 'W0VR9RgJVSLeWHE/fP0YZYo8vvmwgJwffTNDIZDjF+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}