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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d100e66d6e8ae7ca75d659c02d218892293ff36313ea8b63c8bee78b686abeb' 
  AND token = 'DxjOebxShDBWdG/NvBBS9qwOZSCEAdmXhsZIJdeKjxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}