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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3472c9aa5e4c7ade9135ca3d653a22cc59d1e3e5b77fb5faf5565da8b2391215' 
  AND token = 'H6JaLAr4XWEcZMlIF2Y8QdWKPoboVR9+E5bFqRgiN9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}