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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71dc8f6c75c395e954b564acb84361dc7d4c17921c991cad2216c418536bb5c9' 
  AND token = '2U1UMJIOmYWrFzNRhvPMgrs9vTZmuCaEsZ80bOEbLgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}