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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b215931964c8d8109704d08fd4f79fc90ad493e6bb5bdbf1a40fa80779f7d317' 
  AND token = 'FJbhwdaXYde/6gdrR409PhXkCO3NHa5r8evtWqr6PVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}