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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8ec8c446249e31e78ae7ea1488b5582e9f239648e54bdc699c4c1e5dfb734d' 
  AND token = 'TM2pWTa/P896VBB7GXEcbqX16jkfYHRjIi9ydVv6JY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}