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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13e04702c9c53a2469335a4dc225e5aed09de7483e2879856a4fa2bfbf292e1' 
  AND token = 'GEOplst56w5sPYS03VUbee0uTr5JbRNpafiWdF3lCiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}