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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4129b7f634f6328bc15820350c287c15c1b876451bd58fa17a6f7238bccc1a77' 
  AND token = 'Syi4hwTNbmraTuja5VL45Mbo0St79PM4o5F60yCDuVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}