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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f14efea4005123b2114f1aa3948ba58c27dd8d24224601038fcd067ad2b0e097' 
  AND token = 'MY0nk+mXAEMGmxDWyegBhsTVg6SArrI2EoTeeF/ByOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}