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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63339b83765d4246871e699601fb9e301d8a58d27f1aa0e4dc6d2750bd60153' 
  AND token = 'CY/EKB7TXNaiW3JSY7AUyBwAc6iYlMTEf8Jmh/bdu2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}