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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b6c22be5d7c42b932e4cd5651c9d5d60b24d51c7f230d2fc5b7c37cf6866e30' 
  AND token = 'ewxrZXc0k93pkOFixmLLU4Vnl4GapIV27C4MlQPxaoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}