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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74fddee901b346f0b8e6c94f3b47e88f925b336a99f453e65cccf5207ff28ea' 
  AND token = '/SDXQcweVyCi/M7F/wJ+zzSBZ5KzDg10nSbQx4WWe/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}