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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44b8d5d4b0ec76f857c94e400ab233c419e23f7da0ba435c9faac2b552a1ff8d' 
  AND token = 'VNT/5wQ+aDx4UfJTAifWcbXyyKULDLwNvvGjoUl8084=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}