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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89d5369b045dfe49cceba08a0b3502281b1e0c2665e99b377b7e5b180d0607a3' 
  AND token = 'dhxHVysq4U8rckiG66I2yO//doXaUTCbv1ShW6Qs5qI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}