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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23acc62261aec7f9c4dd25a1195b0c50d4849a985791b35f9bbbb4033bf90589' 
  AND token = 'LzJOAh4/w0JO5JArb124RtDL9aOhds5AeUMRhRS+Afg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}