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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c72a7b80497798d2441b96e237e438c3df860ecd7ba73222ee0120d268f7eaf' 
  AND token = '/c763iDZpDtcult6RobQr7r6MPXRVYqrID7227mcI+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}