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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c715f4427148edc1408bab72a3357a56b4b0ed4c3b731592f84062aadb95de71' 
  AND token = 'C2XWSW3vpwQzzTQl4RT46PW89JaqfUzUJ5Xlp6GTIak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}