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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c221bd302560196f65d01dd5f068cd11c5aaa6ec2c5767e6d115de5d3e6a282' 
  AND token = 'LKBDQrJc50qoNH5aVuQJh3USjuQRs0DNoXTqoM15w7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}