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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be8c9d1f6b40bcdef786c9f6bf9e3a6e798efb1e776a553d1cce712bc7adbf7' 
  AND token = '2HS0LIQl+kXI+pBPubnXwRB4DRMYZwQ+KEzP+4pi5WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}