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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0caa51526178290bb38d5069eab34ecba78bbff8e0fe3334bfedf2cfa9b2100c' 
  AND token = 'UuWVk+s1fWE0669sES8uB1saJc4pLi5bhzxZU9/tdDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}