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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f023e9481f1ab9ced33db0ba1dd4c43e015c4f0cb35b1263465e8225f542e1' 
  AND token = 't4FLEMDqxcVwIsNqlV1OJiIgu4ntJj9hGz9pG/6XTxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}