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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347b3bd6aed6e796c6a72b40ff9c53a1462a630671ec9b0d61a655566af3899b' 
  AND token = 'cf+Ps7qNxJAyGNUkZbxjIoKoJ0szReH5OSsFDJ18EVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}