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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50240b2eee3244f7c2a194954ba8c887587db32d8a5e536143c80aa30339a34' 
  AND token = 's3GjZk9vlK3rM/+mvp/yd25sQXDMMDf6dQTVW/ddTF4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}