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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38a0aceef2b4b5d37107cc555e2adbcd46ba379953e482f46c5671febea99644' 
  AND token = 'iRg1z5iETf1u3uUhxxmPG4+JsrELOffI5FySPDUO9wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}