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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e770def16839ec7a97a17dd4905c9223e8dd37d188dabb9bfa3d5ab91d1e506' 
  AND token = 'yOTlcm1lBJ+e9fqmWme7qN+IvY1kosCKB1IRD+QYvgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}