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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d6a67c322b6c47515f95b01a788070a14c2879a2cdfcffc5d800697081f281c' 
  AND token = 'jfW05YqXPycPvsoPdK020Ol3ZGYwRuJApdCs3YS9lB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}