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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73572dd8b356ea5e6fc9c7a953fbd3536ce31226b554da6a5a7fe15786229f54' 
  AND token = '0OrDnMa+wy+ECxMgCT03Gu5QIkE1/NWn6qhKWlj8Wgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}