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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17b45f5f9ee5682c84b53820270b15a6eeb9c5f61031b5824d66aa1c80ae1cab' 
  AND token = 'AbwF0DDwrr1yi++zQ+AeACCVDSvF0dxfzeNWXf4thrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}